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| 1721 | Cartaret |  |
| London Appointed Secretary of State, 1st term |
| 1742 | Cartaret | |
| London Appointed Secretary of State, 2nd term |
| 1756 | Pitt the Elder, William | |
| Appointed Secretary of State |
| 1757 | Pitt the Elder, William | |
| Appointed Secretary of State |
| 1762 | Grenville, George Nugent Temple | |
| London Appointed Secretary of State |
| 1762 | Montague Dunk | |
| London Appointed Secretary of State |
| 1765 | Grafton | |
| London Appointed Secretary of State for the Northern Department |
| 1771 | Montague Dunk | |
| London Appointed Secretary of State |
| 1782 | Holland | |
| London Serves under Rockingham but resigns when he is succeeded by Shelburne |
| 1905 | Gladstone, William Ewart | |
| London Appointed Secretary of State for Home Affairs |
| 1905 | Hope | |
London Appointed Secretary of State for Scotland  |
| 1924 | Birkenhead, Frederick Edwin | |
London Appointed Secretary of State for India  |
| 1940 | Amery, Leopold | |
| London Appointed Secretary of State for India & Burma |
| 1967 | Shore, Peter | |
| London Appointed Secretary of State |
| 1970 | Ridley, Nicholas | |
| Appointed Under Secretary of State for Trade & Indus try |
| 1972 | Whitelaw | |
| 24th Mar London Appointed Secretary of State |
| 1972 | Whitelaw, William | |
| 24th Mar London Appointed Secretary of State for Northern Ireland |
| 1974 | Williams, Shirley | |
| 5th Mar London Appointed Secretary of State for Prices & Consumer Protection |
| 1983 | Walker, Peter | |
| 10th June London Appointed Secretary of State for Energy |
| 2001 | Prescott, John | |
| London Appointed First Secretary of State |
