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| 1500 | Birth Spain |  |
| Castile Birth of Charles V, son of Philip I of Castile |
| 1506 | Succession Spain |  |
| Burgundy Inherits Burgundy |
| Succeeds as King of the Netherlands |
| 1516 | Succession Spain |  |
| Rules Spain as Charles I 1516-1556 |
| Succeeds as King of Spain, as Charles I, 1516-1556 |
| 1518 | Diplomacy Spain |  |
| A peace treaty with Charles of Spain recognizes Navarre as part of Spain |
| 1518 | Treaty of London Spain |  |
| London Calls upon Henry VIII's alliance against French aggression in Navarre |
| London Henry VIII prefers reconciliation between Charles & Francis to the treaty of London |
| 1519 | Succession Spain |  |
| Succeeds as Holy Roman Emperor |
| 28th June Succeeds as Holy Roman Emperor |
| 1520 | Coronation Spain |  |
| 26th Oct Crowned Emperor in France |
| 1520 | Diplomacy Spain |  |
| 26th May Dover Meets Henry VIII & spends three days with Henry & Catherine in Canterbury |
| 14th July Calais Henry VIII & Emperor Charles agree not to sign a new alliance with France for 2 yrs |
| 1520 | Lutheranism Spain |  |
| 28th Sep Issues a decree suppressing Lutheranism in the Netherlands |
| 1520 | Succession Spain |  |
| Succeeds as Holy Roman Emperor |
| 1521 | Alliance Spain |  |
| 12th Aug Bruges Meets Wolsey in Bruges where the terms of a possible alliance are discussed |
| 1521 | Diet Worms Spain |  |
| Worms Establishes the Austrian branch of the Dynasty |
| Worms Presides over the Diet of Worms but Luther refuses to retract his protests |
| Worms Transfers the hereditary Habsburg lands within the Empire to his brother Ferdinand |
| 1521 | Edict Worms Spain |  |
| May Worms Charles issues the Edict of Worms , declaring Martin Luther an outlaw, banning his writings, and requiring his arrest: "We want him to be apprehended and punished as a notorious heretic" |
| 1521 | Succession Spain |  |
| Charles establishes the Austrian branch of the Habsburg Dynasty at the Diet of Worms |
| Charles transfers the hereditary Habsburg lands to his brother Ferdinand |
| 1521 | Trial Spain |  |
| Worms Luther is tried before the Emperor at the Diet of Worms & given an Empire ban |
| 1522 | Diplomacy Spain |  |
| Greenwich Charles V visits England & stays at Greenwich |
| 1525 | Battle of Pavia Spain |  |
| 14th Feb Pavia A birthday gift was the person of the King of France, Spanish hegemony in Italy dates from the battle of Pavia |
| 14th Feb Pavia Charles V, the Holy Roman Emperor, defeats Francis I, King of France, taking him prisoner to Spain |
| 14th Feb Pavia Francis I is captured in Lombardy by the Viceroy of Naples in a war against Charles V |
| 1525 | Rule of Italy Spain |  |
| 14th Feb Pavia A birthday gift was the person of the King of France, Spanish hegemony in Italy dates from the battle of Pavia |
| 1526 | Capture Spain |  |
| 14th Jan Artois Gains Artois from France |
| 14th Jan Burgundy Gains Burgundy from France |
| 14th Jan Artois Gains Flanders from France |
| 1526 | Declaration of War Spain |  |
| Allied with the Pope, Bavaria & Protestant Princes |
| Fought between the Habsburg Charles V, Spain and the Holy Roman Empire, & the League of Cognac, an alliance including France, Pope Clement VII, the Republic of Venice, England, the Duchy of Milan & Florence |
| 1526 | Invasion of Hungary Spain |  |
| Turkey captures most of Hungary |
| 1526 | Invasion of Lombardy Spain |  |
| Lombardy The League of Cognac quickly seizes Lodi, but Imperial troops march into Lombardy and soon force Sforza to abandon Milan |
| 1526 | League Cognac Spain |  |
| 22nd May Madrid Francis I renounces the Treaty of Madrid as it was made under duress |
| 22nd May Cognac The League of Cognac is formed against Charles V |
| 22nd May Cognac The League of Cognac is formed with the Pope, Milan, Venice, & Florence |
| 1526 | League of Cognac Spain |  |
| Fought between the Habsburg Charles V, Spain and the Holy Roman Empire, & the League of Cognac, an alliance including France, Pope Clement VII, the Republic of Venice, England, the Duchy of Milan & Florence |
| Shocked by the defeat of the French in the Italian War of 1521, Clement, together with the Republic of Venice, organizes an alliance to drive the Habsburg powers-Spain and the Holy Roman Empire-from Italy |
| 1526 | Marriage Spain |  |
| Marries Isabella of Portugal |
| 1526 | Rule of Artois Spain |  |
| 14th Jan Artois Under the treaty of Madrid Francis surrenders Burgundy, Artois & Flanders to Charles V |
| 1526 | Rule of Burgundy Spain |  |
| 14th Jan Burgundy Under the treaty of Madrid Francis surrenders Burgundy, Artois & Flanders to Charles V |
| 1526 | Rule of Flanders Spain |  |
| 14th Jan Flanders Under the treaty of Madrid Francis surrenders Burgundy, Artois & Flanders to Charles V |
| 1526 | Siege of Milan Spain |  |
| Milan The League of Cognac quickly seizes Lodi, but Imperial troops march into Lombardy and soon force Sforza to abandon Milan |
| 1526 | Treaty of Cognac Spain |  |
| Cognac Allies Rome, Venice, the Pope & France against Charles V |
| 1526 | Treaty of Madrid Spain |  |
| 14th Jan Madrid Under the treaty of Madrid Francis gives up all claims in Italy |
| 14th Jan Madrid Under the treaty of Madrid Francis surrenders Burgundy, Artois & Flanders to Charles V |
| 1527 | Alliance Spain |  |
| Rome The Alliance of the League of Cognac is defeated by Charles V |
| 1527 | Invasion of Rome Spain |  |
| Rome Charles V gathers a force of landsknechts under Georg Frundsberg and a Spanish army under Charles of Bourbon, the two forces combine at Piacenza and advance on Rome |
| Rome Francesco Guicciardini, in command of the Papal armies, proves unable to resist and when the Duke of Bourbon is killed, his underpaid army sack the city, forcing the Pope to flee |
| 1527 | Siege of Rome Spain |  |
| Rome Clement VII begs Charles V but it is too late to save Rome |
| Rome Clement VII & Charles V sign a truce |
| Rome Rome & the Vatican are sacked by German Lutheran forces & a council is called |
| Rome The Alliance of the League of Cognac is defeated by Charles V |
| 1529 | Diet Speyer, 2nd Spain |  |
| 16th April Speyer At the 2nd Diet of Speyer the Imperial decree of the 1st Diet is repealed |
| 16th April Speyer Princes are not allowed to decide the religious allegiance of their states |
| 1529 | Marriage Spain |  |
| 16th July Influences his nephew Clement VII in refusing to annul Henry VIII's marriage |
| 1529 | Peace Spain |  |
| 29th June Makes peace with Pope Clement VII |
| 1529 | Treaty of Barcelona Spain |  |
| 29th June Barcelona Francis surrenders his rights to Artois , Flanders , and Tournai, and is obliged to pay a ransom of two million golden ‚cus before his sons were to be released |
| 29th June Barcelona Signs a treaty with Pope Clement VII settling their differences |
| 5th Aug Barcelona The final treaty, signed on August 5, removes France from the war, leaving Venice, Florence, and the Pope alone against Charles |
| 1530 | Confession Augsburg Spain |  |
| 25th June Augsburg Recognizes the Augsberg Confession & the Catholic faith |
| 1530 | Coronation Spain |  |
| 24th Feb Bologna Spain's Carlos I is crowned Holy Roman Emperor Charles V by Pope Clement VII in the last coronation of a German King by a Pope |
| 1530 | Diet Augsburg Spain |  |
| 25th June Augsburg Charles failures to destroy Protestantism in the Empire |
| 25th June Augsburg Defends the unity of the Empire by coming to terms with the Protestants |
| 25th June Augsburg Recognizes the Augsberg Confession & the Catholic faith |
| 25th June Augsburg States that the religion of the ruler becomes the religion of the state |
| 25th June Augsburg The Protestants aly with Charles V against the Turks |
| 1530 | League Schmalkaldic Spain |  |
| Rejects the Protestant Confession Augustana |
| The Protestant Imperial Estates form the Schmalkaldic League |
| 1530 | Peace Spain |  |
| Nuremburg Makes peace with the Protestants |
| 1530 | Rule of Malta St John Spain |  |
| Malta Grants the knights of St John permission to settle on the Island of Malta |
| 1531 | Election Spain |  |
| 5th Jan Secures the election of his younger brother Ferdinand as King of the Romans |
| 1531 | Marriage Spain |  |
| Marries his daughter to Alessandro de Medici & makes him Duke of Florence |
| 11th Mar Writes Thomas More an appreciative letter for his support of Queen Catherine |
| 1531 | Protestantism Spain |  |
| Prohibits the adoption of Protestantism in The Netherlands |
| 1532 | Invasion of Austria Spain |  |
| June Vienna Moves to defend Vienna |
| 25th June Belgrade The Turks launches an invasion force from Belgrade |
| 1532 | Peace Spain |  |
| 23rd June Nuremberg Germa Protestant Princes are granted freedom of worship for their support against the Turks |
| 1544 | Battle of Certesole Spain |  |
| 14th April Certesole The Imperial Army of Charles V is defeated by the French south of Turin |
| 1544 | Peace Spain |  |
| 18th Sep Crespy Charles V returns Burgundy |
| 18th Sep Crespy Francis I promises help against the Protestant Estates of the Empire & gives up Naples |
| 1544 | Rule of Burgundy Spain |  |
| 18th Sep Burgundy Under the treaty of Crespy Charles V renounces his claim to Burgundy |
| 1544 | Rule of Milan Spain |  |
| 18th Sep Milan Keeps Under the terms of the Peace of Crespy Charles V keeps Milan |
| 1544 | Rule of Naples Spain |  |
| 18th Sep Naples Under the Peace of Crespy Francis I gives up Naples |
| 1544 | Siege of Paris Spain |  |
| 14th Sep Paris Charles V is joined by English troops in his assault on Paris |
| 1544 | Treaty of Crepy en Valois Spain |  |
| Crepy en Valois Charles V & Francois I make peace in the treaty of Crepy-en-Valois |
| 18th Sep Crespy Charles V renounces his claim to Burgundy but keeps Milan |
| 18th Sep Crespy Ends The treaty of Crespy ends the Schmalkaldic wars |
| 1545 | Spain Turkey War Spain |  |
| Adrianople Charles V & Suleyman make peace in the treaty of Adrianople |
| 1548 | Diet Augsburg Spain |  |
| 30th June Augsburg Proclaims the Augsburg Interim, a failed attempt to unite Catholics & Protestants |
| 1548 | Interim Augsburg Spain |  |
| 30th June Augsburg Defines a form of Catholicism acceptable to Protestants |
| 30th June Augsburg Rejected by most Protestant Princes & only accepted by Pope Paul in 1549 |
| 30th June Augsburg The laity can receive the Communion Cup & Protestant ministers can keep their wives |
| 1552 | Interim Augsburg Spain |  |
| Augsburg A truce between Charles V & the Schmaldic League |
| 1552 | Siege of Metz Spain |  |
| Oct Metz Tries to recapture Lorraine but is repulsed at Metz |
| 1553 | Invasion of Picardy Spain |  |
| Picardy Commences a failed attempt to invade Picardy |
| 1554 | Battle of Renty Spain |  |
| 12th Aug Renty Defeated by the French who end Charles ' invasion of Picardy |
| 1555 | Abdication Spain |  |
| Divides lands between the Spanish & Austrian Habsburgs |
| 1555 | Peace Spain |  |
| Augsburg A religious settlement following the Diet of Augsburg |
| Augsburg Princes in the Empire have a right to impose their religion on their subjects |
| 1555 | Rule of Holland Spain |  |
| 25th Oct Philip II is given the government of The Netherlands by his father Charles V |
| 1556 | Abdication Spain |  |
| Vaucelles Charles V fails in battle & is forced to sign the Peace of Vaucelles then abdicates |
| Charles V fails in battle & is forced to sign the Peace of Vaucelles then abdicates |
| Charles V's brother succeeds as Emperor & his son Philip II succeeds in Spain |
| Ferdinand I becomes Emperor & rules Austria, Hungary & Bohemia |
| Philip II retains Spain, Italy & The Netherlands |
| 1556 | Peace Spain |  |
| Vaucelles Charles V fails in battle & is forced to sign the Peace of Vaucelles then abdicates |
| 1556 | Treaty of Vaucelles Spain |  |
| Vaucelles Charles V fails in battle & is forced to sign the Peace of Vaucelles then abdicates |
| 1558 | Death Spain |  |
| 21st Sep Death of Charles V |